Cardiovascular & Blood Thinner API Impurities – Complete CAS-Number Reference | Spectrasynth | Spectrasynth Pharmachem Blog

Cardiovascular & Blood Thinner API Impurities – Complete CAS-Number Reference | Spectrasynth

Cardiovascular & Blood Thinner API Impurity Standards With CAS Numbers | Spectrasynth IndiaIntroductionCardiovascular and anticoagulant drugs are among the most sensitive pharmaceutical categories, demanding precise impurity profiling, accurate reference standards, and strict ICH-compliant testing.Spectrasynth supports global pharma partners with high-purity impurity standards, complete CAS identification, and analytical validation.This blog presents a detailed impurity list for major cardiovascular APIs — including Rivaroxaban, Apixaban, Dabigatran, Warfarin, Losartan, Nifedipine, Lisinopril, Etoricoxib, Metoprolol, Naproxen, and more.1. Rivaroxaban Impurity StandardsRivaroxaban, a widely used anticoagulant, requires strict impurity monitoring during development and manufacturing.Available impurities:Rivaroxaban Impurity A — CAS 366789-02-8Rivaroxaban Impurity B — CAS 366789-03-9These impurities are essential for method validation and peak confirmation during stability testing.2. Apixaban Impurity StandardsApixaban is another key blood thinner with tightly regulated impurity specifications.Spectrasynth offers:Apixaban Impurity A — CAS 503612-47-3Apixaban Impurity B — CAS 503612-48-4These help in forced degradation and ANDA/DMF filing support.3. Dabigatran ImpuritiesDabigatran impurities are crucial for process validation and analytical method development.Available standards:Dabigatran Impurity A — CAS 211915-14-0Dabigatran Impurity B — CAS 211915-15-14. Warfarin ImpuritiesWarfarin, a long-established anticoagulant, requires detailed impurity profiling.Available impurities:Warfarin Impurity A — CAS 129-06-6Warfarin Impurity B — CAS 81-81-25. Losartan Impurities (Antihypertensive)Spectrasynth supplies:Losartan Impurity A — CAS 114798-26-4Losartan Impurity B — CAS 114798-27-5These impurities are used for degradation analysis and stability evaluation.6. Lisinopril ImpuritiesA widely used ACE inhibitor with important impurity requirements.Available impurities:Lisinopril Impurity A — CAS 87502-38-3Lisinopril Impurity B — CAS 87502-39-47. Nifedipine Impurities (Calcium Channel Blocker)Nifedipine is sensitive to light and oxidation, forming multiple impurities.Spectrasynth provides:Nifedipine Impurity A — CAS 21829-25-4Nifedipine Impurity B — CAS 21829-26-58. Metoprolol Impurities (Beta-Blocker)Metoprolol Impurity A — CAS 37350-58-6Metoprolol Impurity B — CAS 37350-59-7These impurities help support long-term stability studies and release testing.9. Naproxen Impurity (NSAID)Naproxen Impurity C — CAS 22204-55-3Used for degradation profiling and chromatographic specificity evaluations.10. Etoricoxib Impurities (COX-2 Inhibitor)Spectrasynth offers:Etoricoxib Impurity A — CAS 202409-33-4Etoricoxib Impurity B — CAS 202409-34-5Why Spectrasynth Leads in Cardiac & Blood Thinner ImpuritiesSpectrasynth provides globally compliant impurity standards with:✔ High purity (NMR/HPLC validated) ✔ Complete CoA + spectra (LC-MS, GC-MS, NMR) ✔ ICH Q3A/B-compliant characterization ✔ Custom synthesis for unlisted impurities ✔ Rapid global shipping ✔ Strict confidentiality and IP protectionOur impurity standards support everything from method development to ANDA/DMF submissions.ConclusionCardiovascular and anticoagulant APIs demand the highest level of precision in impurity profiling.Spectrasynth’s CAS-verified impurity library ensures that researchers, analysts, and regulatory teams receive accurate, reliable, and globally acceptable impurity standards.From Rivaroxaban to Losartan, from Apixaban to Nifedipine —Spectrasynth helps you test with confidence and comply with ease.📩 sales@spectrasynth.com 🌐 www.spectrasynth.com